Opportunity Information: Apply for PAR 22 081
The Limited Competition: Basic Instrumentation Grant (BIG) Program (PAR 22 081) is a National Institutes of Health (NIH) discretionary grant opportunity designed to help research institutions buy a single expensive, specialized piece of commercially available scientific equipment, or an integrated instrumentation system. The intent is to strengthen shared research capacity by supporting instruments that will be used by a group of NIH-supported investigators, rather than funding individual research projects or new instrument development. Consistent with the notice title, this opportunity is not intended to support clinical trials.
A defining feature of this program is that it is limited to institutions with relatively less recent large NIH S10 instrumentation support. To be eligible, an institution must not have received S10 instrumentation funding of $250,001 or more in any of the prior three federal fiscal years tied to the chosen application due date. NIH specifies how to determine the relevant three-year lookback window for each due date: for applications due June 1, 2022, institutions must review S10 awards from FY 2019 through FY 2021; for applications due June 1, 2023, the applicable window is FY 2020 through FY 2022; and for applications due June 3, 2024, the applicable window is FY 2021 through FY 2023. This eligibility rule is meant to broaden access to instrumentation funding by prioritizing institutions that have not recently received comparatively large S10 instrumentation awards.
Funding under BIG has a minimum award size of $25,000 and a maximum award of $250,000. While there is no stated maximum purchase price for the instrument itself, NIH will not provide more than $250,000 through this mechanism, meaning any remaining costs would need to be covered by other non-federal or institutional sources if the total price exceeds the award cap. The program focuses on acquiring established, commercially available equipment, and examples of supported instruments include (but are not limited to) basic cell sorters, confocal microscopes, ultramicrotomes, gel imaging systems, and computer systems used for research instrumentation needs.
Eligible applicants include a broad set of U.S.-based organizations such as public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (including both 501(c)(3) and non-501(c)(3) nonprofits). The opportunity also explicitly highlights eligibility for several categories of institutions often targeted for capacity-building and broader participation, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). At the same time, it clearly restricts foreign involvement: non-U.S. (foreign) institutions cannot apply, non-U.S. components of U.S. organizations are not eligible, and foreign components as defined by the NIH Grants Policy Statement are not allowed.
Administratively, this is an NIH grant in the health funding activity category, associated with CFDA numbers 93.351 and 93.859. The opportunity was created on January 7, 2022, and lists an original closing date of June 3, 2024. In practical terms, institutions considering applying should focus on assembling a justified, shared-use instrument request that supports multiple NIH-funded investigators while also confirming that their institution meets the S10 lookback limitation for the relevant due date and fiscal-year window.Apply for PAR 22 081
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Limited Competition: Basic Instrumentation Grant (BIG) Program (S10 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.351, 93.859.
- This funding opportunity was created on 2022-01-07.
- Applicants must submit their applications by 2024-06-03. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others.
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Frequently Asked Questions (FAQs)
What is the Limited Competition: Basic Instrumentation Grant (BIG) Program (PAR-22-081)?
The Limited Competition: Basic Instrumentation Grant (BIG) Program (PAR-22-081) is a discretionary National Institutes of Health (NIH) grant opportunity intended to help research institutions purchase a single expensive, specialized piece of commercially available scientific equipment or an integrated instrumentation system. The program is focused on strengthening shared research capacity by supporting instruments used by a group of NIH-supported investigators.
What does this program fund?
This program supports the acquisition of one commercially available, specialized scientific instrument or an integrated instrumentation system intended for shared use by multiple NIH-supported investigators. It is designed to enhance shared research infrastructure rather than support individual research projects.
What does this program not fund?
Based on the notice title and stated intent, this opportunity is not intended to support clinical trials. It is also not intended to fund individual research projects or to support new instrument development; the emphasis is on established, commercially available equipment.
Is this a limited competition opportunity?
Yes. A defining feature is that it is limited to institutions that have had relatively less recent large NIH S10 instrumentation support, as determined by a specific three-federal-fiscal-year lookback rule tied to the application due date.
What is the key institutional eligibility restriction related to prior S10 funding?
To be eligible, an institution must not have received S10 instrumentation funding of $250,001 or more in any of the prior three federal fiscal years tied to the chosen application due date.
How do institutions determine the relevant three-year S10 lookback window?
NIH specifies the three-year lookback window by application due date:
- For applications due June 1, 2022: review S10 awards from FY 2019 through FY 2021.
- For applications due June 1, 2023: review S10 awards from FY 2020 through FY 2022.
- For applications due June 3, 2024: review S10 awards from FY 2021 through FY 2023.
Why does the program include the S10 lookback limitation?
The eligibility rule is meant to broaden access to instrumentation funding by prioritizing institutions that have not recently received comparatively large S10 instrumentation awards.
What is the minimum and maximum award size under BIG?
The minimum award size is $25,000 and the maximum award size is $250,000.
Is there a maximum purchase price for the instrument itself?
No maximum purchase price is stated for the instrument itself. However, NIH will not provide more than $250,000 through this mechanism.
If the instrument costs more than $250,000, can an institution still apply?
The opportunity caps NIH support at $250,000. If the total purchase price exceeds that amount, any remaining costs would need to be covered by other non-federal or institutional sources.
What types of instruments are examples of what BIG may support?
Examples listed include (but are not limited to) basic cell sorters, confocal microscopes, ultramicrotomes, gel imaging systems, and computer systems used for research instrumentation needs.
Does the program support development of new instruments?
No. The program focuses on acquiring established, commercially available equipment rather than developing new instrumentation.
Who is expected to use the instrument funded through this program?
The instrument is intended to be used by a group of NIH-supported investigators. The program is designed to strengthen shared research capacity rather than provide equipment for a single investigator or a single research project.
What organizations are eligible to apply?
Eligible applicants include U.S.-based organizations such as public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (including both 501(c)(3) and non-501(c)(3) nonprofits).
Are any specific categories of institutions explicitly highlighted as eligible?
Yes. The opportunity explicitly highlights eligibility for Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).
Are foreign (non-U.S.) institutions eligible to apply?
No. Non-U.S. (foreign) institutions cannot apply under this opportunity.
Are non-U.S. components of U.S. organizations eligible?
No. Non-U.S. components of U.S. organizations are not eligible.
Are foreign components allowed under this opportunity?
No. Foreign components, as defined by the NIH Grants Policy Statement, are not allowed.
Which federal program identifiers are associated with this opportunity?
This NIH grant opportunity is associated with CFDA numbers 93.351 and 93.859 and is in the health funding activity category.
When was this opportunity created and what is the listed closing date?
The opportunity was created on January 7, 2022, and lists an original closing date of June 3, 2024.
What should institutions focus on when preparing to apply?
Institutions should focus on assembling a justified, shared-use instrument request that supports multiple NIH-funded investigators. They should also confirm institutional eligibility by verifying that they meet the S10 lookback limitation for the relevant due date and its associated fiscal-year window.
Does this grant support clinical trials?
No. Consistent with the notice title and stated intent, this opportunity is not intended to support clinical trials.
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