Opportunity Information: Apply for RFA CK 21 002
The grant opportunity titled "Emerging Infections Network - Research for Preventing, Detecting, and Managing Travelers who Acquire Infectious Diseases Abroad" (Funding Opportunity Number RFA CK 21 002) is a CDC cooperative agreement designed to support applied research that strengthens how the United States prevents, identifies, and manages infectious diseases acquired during international travel. At its core, the program is aimed at improving real-world clinical and public health responses when travelers become sick during travel or after returning home, with the broader goal of improving U.S. global health security by reducing the risk that travel-associated infections go undetected, are mismanaged, or contribute to wider spread.
The research focus is specifically built around travel and tropical medicine providers and networks that can actively participate in studying travel-associated infections. The funded work is expected to generate practical evidence on several key areas: which disease prevention strategies are most effective for travelers, what the true burden and severity of these infections look like in clinical practice, which diagnostic approaches perform best (including identifying optimal testing strategies and when they should be used), which treatment interventions lead to better outcomes, and what short- and long-term outcomes patients experience. A major theme is producing information that is usable in clinics and health systems, not just theoretical, so that providers can make faster and more accurate decisions and public health partners can better interpret and act on clinical signals.
A central selling point of the opportunity is that it "bridges the gap between clinical medicine and public health." In practice, that means the research should connect what clinicians see at the bedside with surveillance, situational awareness, and response activities that protect broader communities. The intention is to improve patient care through better evidence on the natural history of travel-related infectious diseases, while also making it easier to implement best practices for diagnostics and treatment. By building stronger links between provider-based data and public health action, the program supports earlier detection of emerging or unusual infections, clearer understanding of transmission risks, and more consistent management approaches across different settings.
Administratively, this is a discretionary funding opportunity using a cooperative agreement mechanism, which typically signals substantial involvement by the CDC during the project period, such as collaboration on technical direction, alignment with national priorities, and coordination across networks. It falls under the health funding activity category and lists CFDA numbers 93.084 and 93.860. The opportunity anticipated one award with an award ceiling of $1,500,000, indicating a single, relatively large project intended to serve as a national or multi-site effort rather than many smaller independent projects.
Eligibility is broad and includes multiple levels of government (state, county, city/township, and special district governments), public and state-controlled institutions of higher education, private institutions of higher education, independent school districts, federally recognized Native American tribal governments and other tribal organizations, public housing authorities/Indian housing authorities, and nonprofit organizations both with and without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories). The sponsoring agency is the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), with the notice published through CDC ERA. The notice was created on September 30, 2020, and the original application deadline was December 18, 2020, with electronic submissions due by 5:00 p.m. Eastern Time.
Overall, the opportunity is best understood as funding a coordinated research effort that leverages travel and tropical medicine clinical capacity to answer high-impact questions about imported and travel-associated infections. The expected output is evidence that improves prevention guidance for travelers, strengthens diagnostic and treatment decision-making for clinicians, and enhances public health readiness by turning clinical observations into actionable insights that help protect the U.S. from emerging infectious threats linked to global travel.Apply for RFA CK 21 002
- The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Emerging Infections Network - Research for Preventing, Detecting, and Managing Travelers who Acquire Infectious Diseases Abroad" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.084, 93.860.
- This funding opportunity was created on Sep 30, 2020.
- Applicants must submit their applications by Dec 18, 2020 Electronically submitted applications must be submitted no later than 500 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,500,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education.
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