Core Centers for Clinical Research (CCCR) (P30)- Clinical Trial Not Allowed | RFA AR 22 002

Opportunity Information: Apply for RFA AR 22 002

The Core Centers for Clinical Research (CCCR) (P30) - Clinical Trial Not Allowed funding opportunity (RFA-AR-22-002) is a National Institutes of Health (NIH) discretionary grant mechanism designed to support centralized, shared research infrastructure through a P30 core center award. As a reissue of the CCCR program, its main purpose is to strengthen and coordinate clinical research capacity by building and sustaining core resources that multiple investigators can use, rather than funding stand-alone, single-project research studies. The emphasis is on creating an organized center structure that improves efficiency, quality, and collaboration across clinical research efforts within an institution or consortium, typically by providing shared services, facilities, expertise, and governance that individual labs or research teams would struggle to maintain on their own.

A key restriction is captured in the title: clinical trials are not allowed under this opportunity. In practice, that means applicants should not propose activities that meet NIH's definition of a clinical trial, such as prospectively assigning human participants to an intervention to evaluate effects on health-related outcomes. Instead, the grant is oriented toward enabling and improving clinical research environments and shared capabilities. Typical P30-style center elements often include administrative leadership, oversight and governance, shared clinical or translational resources, biostatistics or data management support, recruitment or community engagement capacity, regulatory support, informatics, training or enrichment activities, and other core services that facilitate rigorous clinical research without proposing a trial itself as the funded activity.

Eligibility is broad and includes many U.S.-based organization types across government, academia, nonprofit, and industry. Eligible applicants include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized governments; public housing authorities and Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding institutions of higher education when specified); for-profit organizations other than small businesses; and small businesses. The opportunity also explicitly calls out additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISI); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; eligible agencies of the federal government; regional organizations; and U.S. territories or possessions. Together, this reflects NIH's intent to allow a wide range of institutions, including those serving historically underrepresented communities, to compete for center infrastructure funding.

At the same time, there are important limits related to foreign involvement. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply as the applicant organization, and non-domestic components of U.S. organizations are also not eligible to apply. However, foreign components, as defined in the NIH Grants Policy Statement, are allowed. This distinction typically means a U.S. institution must be the applicant and primary awardee, while certain defined foreign collaborations or components may be included if they are justified, appropriately structured, and compliant with NIH policy. In other words, the grant is primarily meant to build U.S.-based center capacity, but it can still support specific foreign component activities when permitted under NIH rules.

From the administrative details provided, this opportunity is cataloged under CFDA number 93.846 and is issued by the National Institutes of Health. The original closing date listed is September 13, 2021, and the opportunity was created on March 19, 2021. The listed award ceiling is $500,000, indicating an upper bound on the amount that may be awarded (often per year, though the precise interpretation depends on the full announcement and budget period structure). The expected number of awards is not specified in the provided data. Overall, the CCCR (P30) program is best understood as NIH support for shared clinical research cores and center governance that enable multiple research projects and investigators, with the explicit requirement that the funded center activities themselves must not include clinical trials.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Core Centers for Clinical Research (CCCR) (P30)- Clinical Trial Not Allowed" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.846.
• This funding opportunity was created on 2021-03-19.
• Applicants must submit their applications by 2021-09-13. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $500,000.00 in funding.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for RFA AR 22 002

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